Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism
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DOI: 10.1021/acschembio.2c00103
Abstract: Inhibitors of the proprotein convertase furin might serve as broad-spectrum antiviral therapeutics. High cellular potency and antiviral activity against acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported for (3,5-dichlorophenyl)pyridine-derived furin inhibitors. Here we characterized… read more here.
Keywords: inhibit furin; molecules inhibit; dichlorophenylpyridine based; mechanism ... See more keywords