Endogenous Proteins Modulation in Live Cells with Small Molecules and Light
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DOI: 10.1002/cbic.202200244
Abstract: Protein modulation by light illumination enables the investigation of biological function in high spatiotemporal precision. Compared to genetic methods, the small molecule approach is uniquely suited for modulating endogenous proteins. Endogenous protein modulation in live… read more here.
Keywords: molecules light; endogenous proteins; live cells; small molecules ... See more keywords
Precision Control of CRISPR-Cas9 Using Small Molecules and Light.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b01202
Abstract: The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system is an adaptive immune system of bacteria that has furnished several RNA-guided DNA endonucleases (e.g., Cas9) that are revolutionizing the field of genome engineering. Cas9 is… read more here.
Keywords: control; small molecules; precision control; molecules light ... See more keywords