Phenotypic Screening for Small Molecules that Protect β-Cells from Glucolipotoxicity.
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DOI: 10.1021/acschembio.2c00052
Abstract: Type 2 diabetes is marked by progressive β-cell failure, leading to loss of β-cell mass. Increased levels of circulating glucose and free fatty acids associated with obesity lead to β-cell glucolipotoxicity. There are currently no… read more here.
Keywords: molecules protect; glucolipotoxicity; cell; screening small ... See more keywords