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The Histone Deacetylase Inhibitor I1 Induces Differentiation of Acute Leukemia Cells With MLL Gene Rearrangements via Epigenetic Modification

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.876076

Abstract: Acute leukemia (AL) is characterized by excessive proliferation and impaired differentiation of leukemic cells. AL includes acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Previous studies have demonstrated that about 10% of AML and… read more here.

Keywords: cell; molm thp; leukemia; acute leukemia ... See more keywords