{Moco}n, (n = 0-8): A general formalism for describing the highly covalent molybdenum cofactor of sulfite oxidase and related Mo enzymes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2022.111801
Abstract: Over 50 molybdenum enzymes in three distinct families (sulfite oxidase, xanthine oxidase, DMSO reductase) are known, and representative X-ray crystal structures are available for all families. Structural analogues that replicate the coordination about the Mo… read more here.
Keywords: oxidase; sulfite oxidase; moco; molybdenum cofactor ... See more keywords
Comparison of molybdenum and rhenium oxo bis-pyrazine-dithiolene complexes - in search of an alternative metal centre for molybdenum cofactor models.
Sign Up to like & getrecommendations! Published in 2019 at "Dalton transactions"
DOI: 10.1039/c8dt04237c
Abstract: A pair of structurally precise analogues of molybdenum and rhenium complexes, [Et4N]/K2[MoO(prdt)2] and K[ReO(prdt)2] (prdt = pyrazine-2,3-dithiolene), were synthesized. These complexes serve as structural models for the active sites of bacterial molybdenum cofactor containing enzymes.… read more here.
Keywords: molybdenum rhenium; molybdenum cofactor; pyrazine dithiolene; metal ... See more keywords
Sulfite Alters the Mitochondrial Network in Molybdenum Cofactor Deficiency
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DOI: 10.3389/fgene.2020.594828
Abstract: Molybdenum cofactor deficiency (MoCD) is an autosomal recessive disorder belonging to the large family of inborn errors in metabolism. Patients typically present with encephalopathy and seizures early after birth and develop severe neurodegeneration within the… read more here.
Keywords: cofactor deficiency; molybdenum cofactor; network; mitochondrial network ... See more keywords
The Molybdenum Cofactor Biosynthesis Network: In vivo Protein-Protein Interactions of an Actin Associated Multi-Protein Complex
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2017.01946
Abstract: Survival of plants and nearly all organisms depends on the pterin based molybdenum cofactor (Moco) as well as its effective biosynthesis and insertion into apo-enzymes. To this end, both the central Moco biosynthesis enzymes are… read more here.
Keywords: protein; biosynthesis; network; molybdenum cofactor ... See more keywords
Physiological Importance of Molybdate Transporter Family 1 in Feeding the Molybdenum Cofactor Biosynthesis Pathway in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27103158
Abstract: Molybdate uptake and molybdenum cofactor (Moco) biosynthesis were investigated in detail in the last few decades. The present study critically reviews our present knowledge about eukaryotic molybdate transporters (MOT) and focuses on the model plant… read more here.
Keywords: biosynthesis; molybdenum cofactor; molybdate; moco biosynthesis ... See more keywords