Editor’s Highlight: Mode of Action Analysis for Rat Hepatocellular Tumors Produced by the Synthetic Pyrethroid Momfluorothrin Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes
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DOI: 10.1093/toxsci/kfx102
Abstract: High dietary levels of momfluorothrin, a nongenotoxic synthetic pyrethroid, induced hepatocellular tumors in male and female Wistar rats in a 2-year bioassay. The mode of action (MOA) for rat hepatocellular tumors was postulated to occur… read more here.
Keywords: momfluorothrin; rat hepatocellular; car; hepatocellular tumors ... See more keywords