Induction of endoplasmic reticulum stress is associated with the anti-tumor activity of monepantel across cancer types.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6021
Abstract: BACKGROUND Monepantel is an anti-helminthic drug that also has anti-cancer properties. Despite several studies over the years, the molecular target of monepantel in mammalian cells is still unknown, and its mechanism-of-action is not fully understood,… read more here.
Keywords: cell; monepantel; cell cycle; activity ... See more keywords
Lack of efficacy of monepantel against trichostrongyle nematodes in a UK sheep flock.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2018.05.013
Abstract: Monepantel resistance was diagnosed during routine monitoring of the effectiveness of a farm's roundworm control strategy. Weaned lambs had become ill thrifty and developed diarrhoea, despite the routine use of monepantel. This clinical presentation was… read more here.
Keywords: efficacy monepantel; trichostrongyle nematodes; efficacy; monepantel trichostrongyle ... See more keywords
Suppressive treatment with monepantel and the fast selection for phenotypically resistant trichostrongylids of sheep
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DOI: 10.1017/s003118202200018x
Abstract: Abstract Abstract Gastrointestinal parasite control has been a major challenge to livestock due to the failure of anthelmintic treatments. Monepantel (MNT) was introduced in 2009 as an alternative treatment option showing a new mechanism of… read more here.
Keywords: every days; monepantel; suppressive treatment; mnt ... See more keywords
Effectiveness of monepantel and levamisole to control gastrointestinal strongylid parasites of sheep
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DOI: 10.14393/bj-v33n3-33325
Abstract: Anthelmintic resistance poses a major challenge to the control of endoparasites in sheep. The recent launch of monepantel may represent an alternative for the treatment of helminth infections. The purpose of this study was to… read more here.
Keywords: control; levamisole control; monepantel; monepantel levamisole ... See more keywords