Risk Assessment and Monitoring of Antibody Responses to Biosimilars in Chronic Inflammatory Diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666171129194044
Abstract: The expiry of the patent of several leading biological medicinal products has led to a surge in the development of 'biosimilar' products. However, in contrast to generic small-molecule medicines, biosimilars are not identical to their… read more here.
Keywords: risk assessment; medicinal products; antibody; assessment monitoring ... See more keywords
Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations
Sign Up to like & getrecommendations! Published in 2017 at "Bioengineering"
DOI: 10.3390/bioengineering4030065
Abstract: Multi-wavelength fluorescence spectroscopy was evaluated in this work as tool for real-time monitoring of antibody aggregation in CHO fed-batch cultivations via partial least square (PLS) modeling. Therefore, we used the extrinsic fluorescence dyes 1-anilinonaphthalene-8-sulfonate (ANS),… read more here.
Keywords: antibody aggregation; aggregation cho; monitoring antibody; fluorescence ... See more keywords