Real-time monitoring of caspase-3/8 activity by self-assembling nanofiber probes in living cells.
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DOI: 10.1039/d0cc07821b
Abstract: Caspase-3/8 are key members of the cysteine-aspartyl protease family with pivotal roles in apoptosis. We have designed and synthesized self-assembling probes, Nap-GFFpYDEVD-AFC and Nap-GFFpYIETD-AFC, with fluorescence 'turn-on' properties for real-time monitoring of Caspase-3/8 activity in… read more here.
Keywords: caspase; time monitoring; self assembling; real time ... See more keywords