Investigating the impact of data monitoring committee recommendations on the probability of trial success.
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DOI: 10.1080/10543406.2024.2430308
Abstract: Determining the probability of success of a clinical trial using a prior distribution on the treatment effect can significantly enhance decision-making by the sponsor. In a group sequential design, the probability of success calculated at… read more here.
Keywords: trial; monitoring committee; probability success; success ... See more keywords