Intramolecular and Intermolecular FRET Sensors for GPCRs - Monitoring Conformational Changes and Beyond.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2017.10.011
Abstract: Within the past decade, a large increase in structural knowledge from crystallographic studies has significantly fostered our understanding of the structural biology of G protein-coupled receptors (GPCRs). However, information on dynamic events upon receptor activation… read more here.
Keywords: monitoring conformational; gpcrs monitoring; intermolecular fret; sensors gpcrs ... See more keywords
Monitoring the Conformational Changes of the Aβ(25−35) Peptide in SDS Micelles: A Matter of Time
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DOI: 10.3390/ijms24020971
Abstract: Alzheimer’s disease is a neurodegenerative disease characterized by the formation of amyloid plaques constituted prevalently by amyloid peptides. Due to the well-known challenges related to the study in solution of these peptides, several membrane-mimicking systems… read more here.
Keywords: sds micelles; time; changes peptide; conformational changes ... See more keywords