Therapeutic drug monitoring of monoclonal antibodies: Applicability based on their pharmacokinetic properties.
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DOI: 10.1016/j.dmpk.2018.11.003
Abstract: Monoclonal antibodies (mAbs) have dramatically improved clinical outcomes for inflammatory and malignant diseases. The elimination route of mAbs is cellular uptake by nonspecific pinocytosis or receptor-mediated endocytosis followed by proteolytic degradation which is protected by… read more here.
Keywords: monoclonal antibodies; mabs; drug; therapeutic drug ... See more keywords