FRET monitoring of a nonribosomal peptide synthetase.
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DOI: 10.1038/nchembio.2435
Abstract: Nonribosomal peptide synthetases (NRPSs) are multidomain enzyme templates for the synthesis of bioactive peptides. Large-scale conformational changes during peptide assembly are obvious from crystal structures, yet their dynamics and coupling to catalysis are poorly understood.… read more here.
Keywords: peptide synthetase; fret monitoring; phenylalanine; monitoring nonribosomal ... See more keywords