Monkeypox Virus and Ophthalmology-A Primer on the 2022 Monkeypox Outbreak and Monkeypox-Related Ophthalmic Disease.
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DOI: 10.1001/jamaophthalmol.2022.4567
Abstract: Importance An ongoing global monkeypox virus outbreak in 2022 includes the US and other nonendemic countries. Monkeypox ophthalmic manifestations may present to the ophthalmologist, or the ophthalmologist may be involved in comanagement. This narrative review… read more here.
Keywords: ophthalmology; outbreak; ophthalmic disease; monkeypox virus ... See more keywords
Genomic annotation and molecular evolution of monkeypox virus outbreak in 2022
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DOI: 10.1002/jmv.28036
Abstract: Monkeypox virus (MPXV) has generally circulated in West and Central Africa since its emergence. Recently, sporadic MPXV infections in several nonendemic countries have attracted widespread attention. Here, we conducted a systematic analysis of the recent… read more here.
Keywords: mpxv 2022; genomic annotation; outbreak; mpxv ... See more keywords
Laboratory validation and clinical performance of a saliva‐based test for monkeypox virus
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DOI: 10.1002/jmv.28191
Abstract: Improved diagnostic tests and accessibility are essential for controlling the outbreak of monkeypox. We describe a saliva‐based polymerase chain reaction (PCR) assay for monkeypox virus, in vitro test performance, and clinical implementation of that assay… read more here.
Keywords: saliva based; performance; monkeypox virus;
The pathophysiological and immunological background of the monkeypox virus infection: An update
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DOI: 10.1002/jmv.28206
Abstract: In addition to the COVID‐19 waves, the globe is facing global monkeypox (MPX) outbreak. MPX is an uncommon zoonotic infection characterized by symptoms similar to smallpox. It is caused by the monkeypox virus (MPXV), a… read more here.
Keywords: pathophysiological immunological; immunological background; infection; monkeypox virus ... See more keywords
Evaluation and validation of an RT‐PCR assay for specific detection of monkeypox virus (MPXV)
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DOI: 10.1002/jmv.28247
Abstract: Monkeypox virus (MPXV) is a zoonotic orthopoxvirus within the Poxviridae family. MPXV is endemic to Central and West Africa. However, the world is currently witnessing an international outbreak with no clear epidemiological links to travel… read more here.
Keywords: virus mpxv; pcr assay; monkeypox virus;
Oropharyngeal samples versus lesion specimens at diagnosis in patients infected with monkeypox virus in Northern France
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DOI: 10.1002/jmv.28276
Abstract: The ongoing outbreak of monkeypox virus (MPXV) is the largest one in historically non‐endemic countries. Early reports described atypical epidemiological and clinical presentations. We investigated MPXV DNA detection in oropharyngeal samples (OPS), and compared the… read more here.
Keywords: virology; lesion; diagnosis patients; monkeypox virus ... See more keywords
Monkeypox outbreak 2022: What we know so far and its potential drug targets and management strategies
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DOI: 10.1002/jmv.28306
Abstract: Monkeypox is a rare zoonotic disease caused by infection with the monkeypox virus. The disease can result in flu‐like symptoms, fever, and a persistent rash. The disease is currently spreading throughout the world and prevention… read more here.
Keywords: potential drug; monkeypox virus; targets management; drug ... See more keywords
CRISPR–Cas12‐based field‐deployable system for rapid detection of synthetic DNA sequence of the monkeypox virus genome
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28385
Abstract: The global outbreak of the monkeypox virus (MPXV) highlights the need for rapid and cost‐effective MPXV detection tools to effectively monitor and control the monkeypox disease. Herein, we demonstrated a portable CRISPR–Cas‐based system for naked‐eye… read more here.
Keywords: crispr cas12; system; detection; monkeypox virus ... See more keywords
Wide mismatches in the sequences of primers and probes for monkeypox virus diagnostic assays
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DOI: 10.1002/jmv.28395
Abstract: Rapid and accurate diagnosis of infections is fundamental to containment of disease. Several monkeypox virus (MPV) real‐time diagnostic assays have been recommended by the CDC; however, the specificity of the primers and probes in these… read more here.
Keywords: diagnostic assays; primers probes; mpv; real time ... See more keywords
Monkeypox virus, herpes simplex virus, and cytomegalovirus skin coinfections
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DOI: 10.1002/jmv.28500
Abstract: We read with interest the recent article entitled "Concomitant diagnosis of sexually transmitted infections and human monkeypox in patients attending a sexual health clinic in Milan, Italy" by Rizzo et al This article is protected… read more here.
Keywords: virus herpes; simplex virus; monkeypox virus; virus ... See more keywords
Ultrastructural analysis of monkeypox virus replication in Vero cells
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DOI: 10.1002/jmv.28536
Abstract: In early May 2022, the first worldwide monkeypox virus (MPXV) outbreak was reported, with different clinical aspects from previously studied human monkeypox infections. Despite monkeypox medical importance, much of its biological aspects remain to be… read more here.
Keywords: replication; vero cells; analysis; monkeypox virus ... See more keywords