Application of Mono‐ and Disaccharides in Drug Targeting and Efficacy
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DOI: 10.1002/cmdc.201700762
Abstract: Carbohydrates and their conjugates play important roles in many biological processes including fertilization, differentiation, development, immune response, and infection. Their activities are largely dependent on the properties of terminal mono‐ or disaccharides. Galactose, mannose, fucose,… read more here.
Keywords: application mono; disaccharides drug; efficacy; drug ... See more keywords
Method development for mono- and disaccharides monitoring in cell culture medium by capillary and microchip electrophoresis.
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DOI: 10.1002/elps.202100213
Abstract: The rapidly growing, competitive biopharmaceutical market requires tight bioprocess monitoring. An integrated, automated platform for the routine on-line/ at-line monitoring of key factors in the cell culture medium could greatly improve process monitoring. Mono- and… read more here.
Keywords: microchip electrophoresis; cell culture; electrophoresis; monitoring ... See more keywords
Anomeric alkylations and acylations of unprotected mono- and disaccharides mediated by pyridoneimine in aqueous solutions.
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DOI: 10.1039/d1cc07056h
Abstract: A site-specific deprotonation followed by alkylations and acylations of sugar hemiacetals to the corresponding alkyl glycosides and acylated sugars in aqueous solutions is disclosed herein. Pyridoneimine as a new base is developed to mediate the… read more here.
Keywords: alkylations acylations; unprotected mono; aqueous solutions; acylations unprotected ... See more keywords