Synthesis and gelation capability of mono- and disubstituted cyclo(L-Glu-L-Glu) derivatives with tyramine, tyrosine and phenylalanine
Sign Up to like & getrecommendations! Published in 2017 at "Colloid and Polymer Science"
DOI: 10.1007/s00396-017-4120-y
Abstract: A series of mono- and disubstituted glutamic cyclic dipeptide derivatives (cyclo(L-Glu-Glu)s) with tyramine, tyrosine, and phenylalanine (3–12) were synthesized and investigated as organo- and hydrogelators. Unexpectedly, both tyramine mono- and disubstituted cyclo(L-Glu-Glu)s showed no gelation… read more here.
Keywords: mono disubstituted; glu glu; tyrosine phenylalanine; glu ... See more keywords
Synthesis of mono- and disubstituted 1,3,4-oxadiazoles (microreview)
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02504-7
Abstract: A brief review of the publications devoted to the synthesis of mono- and disubstituted 1,3,4-oxadiazoles over the last five years is presented. read more here.
Keywords: mono disubstituted; oxadiazoles microreview; disubstituted oxadiazoles; synthesis mono ... See more keywords
The monoamine oxidase inhibition properties of C6-mono- and N3/C6-disubstituted derivatives of 4(3H)-quinazolinone.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.12.030
Abstract: Parkinson's disease is characterised by the death of the nigrostriatal neurons and depletion of striatal dopamine. The standard symptomatic therapy consists of dopamine replacement with l-dopa, the metabolic precursor of dopamine, which represents the most… read more here.
Keywords: mono disubstituted; disubstituted derivatives; derivatives quinazolinone; monoamine oxidase ... See more keywords
Microwave-assisted dealkoxycarbonylation of α-mono- and α,α-disubstituted β-keto- and α-cyanoesters mediated by a silica gel bed
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c7nj04340f
Abstract: A new alternative protocol for the classical Krapcho reaction is reported herein, involving a microwave-assisted method, which replaces the typical aprotic polar solvent with a silica gel support along with the addition of only a… read more here.
Keywords: mono disubstituted; dealkoxycarbonylation mono; microwave assisted; disubstituted keto ... See more keywords
Structure and cytotoxic properties of 1-hydroxy-5-methyl-7-phenylpyrido[3,4-d]pyridazin-4(3H)-one and its mono- and disubstituted ethyl acetates.
Sign Up to like & getrecommendations! Published in 2022 at "Acta crystallographica. Section C, Structural chemistry"
DOI: 10.1107/s2053229622009202
Abstract: Derivatives of pyrido[3,4-d]pyridazine, namely, 1-hydroxy-5-methyl-7-phenylpyrido[3,4-d]pyridazin-4(3H)-one dimethylformamide monosolvate, C14H11N3O2·C3H7NO (2), ethyl [1-(2-ethoxy-2-oxoethoxy)-5-methyl-4-oxo-7-phenyl-3,4-dihydropyrido[3,4-d]pyridazin-3-yl]acetate, C18H17N3O4 (3), and ethyl [(5-methyl-4-oxo-7-phenyl-3,4-dihydropyrido[3,4-d]pyridazin-1-yl)oxy]acetate, C22H23N3O6 (4), were synthesized with the aim of discovering new potential biologically active agents. The properties of all three… read more here.
Keywords: pyridazin one; hydroxy methyl; methyl phenylpyrido; phenylpyrido pyridazin ... See more keywords