Selective synthesis of mono- and di-methylated amines using methanol and sodium azide as C1 and N1 sources
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DOI: 10.1039/c8gc00863a
Abstract: A Ru(II) complex mediated synthesis of various N,N-dimethyl and N-monomethyl amines from organic azides using methanol as a methylating agent is reported. This methodology was successfully applied for a one-pot reaction of bromide derivatives and… read more here.
Keywords: sodium azide; selective synthesis; mono methylated; synthesis mono ... See more keywords
Mono-methylated histones control PARP-1 in chromatin and transcription
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DOI: 10.1101/2023.11.22.568326
Abstract: PARP-1 is central to transcriptional regulation under both normal and stress conditions, with the governing mechanisms yet to be fully understood. Our biochemical and ChIP-seq-based analyses showed that PARP-1 binds specifically to active histone marks,… read more here.
Keywords: methylated histones; parp; heat; heat shock ... See more keywords