LAUSR

Monoallelic IRF5 deficiency in B cells prevents murine lupus

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1 Published in 2021 at "JCI Insight"

DOI: 10.1172/jci.insight.141395

Abstract: Gain-of-function polymorphisms in the transcription factor IFN regulatory factor 5 (IRF5) are associated with an increased risk of developing systemic lupus erythematosus. However, the IRF5-expressing cell type(s) responsible for lupus pathogenesis in vivo is not… read more here.

Keywords: irf5; deficiency cells; monoallelic irf5; murine lupus ... See more keywords