Human-specific mutations in VMAT1 confer functional changes and multi-directional evolution in the regulation of monoamine circuits
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DOI: 10.1186/s12862-019-1543-8
Abstract: BackgroundNeurochemicals like serotonin and dopamine play crucial roles in human cognitive and emotional functions. Vesicular monoamine transporter 1 (VMAT1) transports monoamine neurotransmitters, and its variant (136Thr) is associated with various psychopathological symptoms and reduced monoamine… read more here.
Keywords: evolution; monoamine uptake; functional changes; vmat1 ... See more keywords