Antioxidant and anti‐inflammatory effects of the monocarbonyl curcumin analogs B2BRBC and C66 in monocrotaline‐induced right ventricular hypertrophy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22353
Abstract: For 22 days after monocrotaline injection two groups of rats received either of the monocarbonyl curcumin analogs (2E,6E)‐2,6‐bis(2‐bromobenzylidene)cycloxehanone (B2BrBC) and (2E,6E)‐2,6‐bis([2‐trifluoromethyl]benzylidene)cyclohexanone (C66), and their right ventricle parameters were compared to those from the control and… read more here.
Keywords: monocrotaline; curcumin analogs; b2brbc c66; monocarbonyl curcumin ... See more keywords
Monocarbonyl Curcumin Analogues as Potent Inhibitors against Human Glutathione Transferase P1-1
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DOI: 10.3390/antiox12010063
Abstract: The isoenzyme of human glutathione transferase P1-1 (hGSTP1-1) is involved in multi-drug resistance (MDR) mechanisms in numerous cancer cell lines. In the present study, the inhibition potency of two curcuminoids and eleven monocarbonyl curcumin analogues… read more here.
Keywords: curcumin analogues; monocarbonyl curcumin; glutathione transferase; curcumin ... See more keywords
Synthesis and Biological Evaluation of Hydroxylated Monocarbonyl Curcumin Derivatives as Potential Inducers of Neprilysin Activity
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DOI: 10.3390/biomedicines9080955
Abstract: Background: Alzheimer’s disease (AD) involves impairment of Aβ clearance. Neprilysin (NEP) is the most efficient Aβ peptidase. Enhancement of the activity or expression of NEP may provide a prominent therapeutic strategy against AD. Aims: Ten… read more here.
Keywords: curcumin derivatives; monocarbonyl curcumin; hydroxylated monocarbonyl; synthesis biological ... See more keywords