Monocarbonyl curcuminoids as antituberculosis agents with their moderate in‐vitro metabolic stability on human liver microsomes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22754
Abstract: Tuberculosis, an airborne infectious disease, results in a high morbidity and mortality rate. The continuous emergence of TB resistance strains including MDR (multidrug‐resistant tuberculosis), XDR (extensive drug‐resistant tuberculosis), and especially TDR (totally drug‐resistant tuberculosis) is… read more here.
Keywords: vitro metabolic; metabolic stability; monocarbonyl curcuminoids; tuberculosis ... See more keywords
Monocarbonyl Curcuminoids with Improved Stability as Antibacterial Agents against Staphylococcus aureus and Their Mechanistic Studies
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b02625
Abstract: Curcumin has been known to possess diverse pharmacological effects at relatively nontoxic doses; however, its therapeutic potential is severely restricted because of its low aqueous solubility and poor stability under physiological conditions. To overcome its… read more here.
Keywords: antibacterial agents; stability antibacterial; monocarbonyl curcuminoids; staphylococcus aureus ... See more keywords