Circulating exosomal long noncoding RNA PRINS—First findings in monoclonal gammopathies
Sign Up to like & getrecommendations! Published in 2018 at "Hematological Oncology"
DOI: 10.1002/hon.2554
Abstract: Multiple myeloma is the second most common hematological malignancy characterized by focal lesions of malignant plasma cells in the bone marrow. These lesions contain subclones that directly influence survival of patients. Bone marrow biopsies are… read more here.
Keywords: long noncoding; monoclonal gammopathies; exosomal long; circulating exosomal ... See more keywords
Unraveling the heterogeneity of IgM monoclonal gammopathies: a gene mutational and gene expression study
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Hematology"
DOI: 10.1007/s00277-017-3207-3
Abstract: Immunoglobulin M (IgM) monoclonal gammopathies show considerable variability, involving three different stages of presentation: IgM monoclonal gammopathy of undetermined significance (IgM-MGUS), asymptomatic Waldenström’s macroglobulinemia (AWM), and symptomatic WM (SWM). Despite recent findings about the genomic… read more here.
Keywords: monoclonal gammopathies; igm monoclonal; gene expression; study ... See more keywords
Polyclonal serum free light chain elevation is associated with increased risk of monoclonal gammopathies
Sign Up to like & getrecommendations! Published in 2019 at "Blood Cancer Journal"
DOI: 10.1038/s41408-019-0210-z
Abstract: Monoclonal gammopathies (MG) constitute a spectrum of disorders starting from a monoclonal gammopathy of undetermined significance (MGUS) to active disease requiring therapy such as multiple myeloma. MG are characterized by proliferation of clonal plasma cells… read more here.
Keywords: risk; free light; monoclonal gammopathies; increased risk ... See more keywords
Corneal Densitometry for Quantification of Corneal Deposits in Monoclonal Gammopathies
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DOI: 10.1097/ico.0000000000001078
Abstract: Purpose: To assess the capability of Scheimpflug-based densitometry of the cornea to quantify light chain deposits in patients with active monoclonal gammopathies. Methods: This is a case–control study in which data from a leading tertiary… read more here.
Keywords: corneal; monoclonal gammopathies; annular zone; deposits monoclonal ... See more keywords
Retinal oxygen saturation in monoclonal gammopathies patients: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Acta Ophthalmologica"
DOI: 10.1111/aos.15239
Abstract: The aim of this pilot study was to assess oxygen saturation in retinal blood vessels in patients with monoclonal gammopathies (MGs). read more here.
Keywords: pilot study; monoclonal gammopathies; oxygen saturation;
Use of Clinical Decision Support to Improve the Laboratory Evaluation of Monoclonal Gammopathies.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of clinical pathology"
DOI: 10.1182/blood-2022-159147
Abstract: OBJECTIVES There is considerable variation in ordering practices for the initial laboratory evaluation of monoclonal gammopathies (MGs) despite clear society guidelines to include serum free light chain (sFLC) testing. We assessed the ability of a… read more here.
Keywords: evaluation; laboratory evaluation; clinical decision; monoclonal gammopathies ... See more keywords
Circulating Regulatory T-Cell Number Does Not Predict Prognosis of Monoclonal Gammopathies of Uncertain Significance.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2021038544
Abstract: FOXP3-expressing regulatory T-cells (Tregs), which suppress aberrant immune response against self-antigens, also suppress anti-tumor immune response. It has been shown that there is an increased proportion of Tregs in several different human malignancies, although the… read more here.
Keywords: monoclonal gammopathies; gammopathies uncertain; uncertain significance; predict prognosis ... See more keywords
Impact of viral hepatitis therapy in multiple myeloma and other monoclonal gammopathies linked to hepatitis B or C viruses.
Sign Up to like & getrecommendations! Published in 2023 at "Haematologica"
DOI: 10.3324/haematol.2023.283096
Abstract: Subsets of multiple myeloma (MM) and monoclonal gammopathies of undetermined significance (MGUS) present with a monoclonal immunoglobulin specific for hepatitis C virus (HCV), thus are presumably HCV-driven, and antiviral treatment can lead to the disappearance… read more here.
Keywords: myeloma monoclonal; hbv; monoclonal gammopathies; hepatitis ... See more keywords
Immunoglobulin M Monoclonal Gammopathies of Clinical Significance
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DOI: 10.3389/fonc.2022.905484
Abstract: Immunoglobulin M monoclonal gammopathy of undetermined significance (MGUS) comprises 15-20% of all cases of MGUS. IgM MGUS is distinct from other forms of MGUS in that the typical primary progression events include Waldenstrom macroglobulinaemia and… read more here.
Keywords: clinical significance; igm; monoclonal gammopathies; immunoglobulin monoclonal ... See more keywords
Monoclonal Gammopathies of Renal Significance: Renal Biopsy and Beyond
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DOI: 10.3390/cancers12071741
Abstract: Monoclonal Gammopathies of Renal Significance (MGRS) are a rather heterogeneous group of renal disorders caused by a circulating monoclonal (MC) immunoglobulin (Ig) component, often in the absence of multiple myeloma (MM) or another clinically relevant… read more here.
Keywords: biopsy; monoclonal gammopathies; renal biopsy; gammopathies renal ... See more keywords
Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma
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DOI: 10.3390/cancers13133189
Abstract: Simple Summary Monoclonal gammopathies comprise a spectrum of disorders defined by the clonal proliferation of plasma cells and include monoclonal gammopathy of undetermined significance (MGUS), smoldering MM (SMM) and multiple myeloma (MM), which can also… read more here.
Keywords: mtdnacn; monoclonal gammopathies; myeloma; smm ... See more keywords