Antioxidant and anti‐inflammatory effects of the monocarbonyl curcumin analogs B2BRBC and C66 in monocrotaline‐induced right ventricular hypertrophy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22353
Abstract: For 22 days after monocrotaline injection two groups of rats received either of the monocarbonyl curcumin analogs (2E,6E)‐2,6‐bis(2‐bromobenzylidene)cycloxehanone (B2BrBC) and (2E,6E)‐2,6‐bis([2‐trifluoromethyl]benzylidene)cyclohexanone (C66), and their right ventricle parameters were compared to those from the control and… read more here.
Keywords: monocrotaline; curcumin analogs; b2brbc c66; monocarbonyl curcumin ... See more keywords
Cystamine slows but not inverses the progression of monocrotaline-induced pulmonary arterial hypertension in rats.
Sign Up to like & getrecommendations! Published in 2018 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2017-0720
Abstract: Tissue transglutaminase (TG2) plays an important role in pulmonary arterial hypertension (PAH). Previous research indicate that TG2 and protein serotonylation catalyzed by TG2 are upregulated in PAH. Serotonin transporter inhibitor fluoxetine ameliorates PAH via inhibition… read more here.
Keywords: monocrotaline; tg2; pulmonary arterial; monocrotaline induced ... See more keywords
Inhibitory effects of formononetin on the monocrotaline-induced pulmonary arterial hypertension in rats
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DOI: 10.3892/mmr.2020.10911
Abstract: Pulmonary arterial hypertension (PAH) is a fatal syndrome resulting from enhanced pulmonary arterial pressure and pulmonary vessel resistance. Perivascular inflammation and extracellular matrix deposition are considered to be the crucial pathophysiologic bases of PAH. Formononetin… read more here.
Keywords: pulmonary arterial; monocrotaline; arterial hypertension; collagen type ... See more keywords