Articles with "monocyte chemoattractant" as a keyword



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Monocyte chemoattractant protein 1 as a potential biomarker for immune checkpoint inhibitor‐associated neurotoxicity

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Published in 2023 at "Cancer Medicine"

DOI: 10.1002/cam4.5695

Abstract: Oncological patients can benefit substantially from treatment with immune checkpoint inhibitors (ICI). However, there is a growing awareness of immune‐related adverse events (irAE). Especially ICI‐mediated neurological adverse events (nAE(+)), are tough to diagnose and biomarkers… read more here.

Keywords: protein potential; immune checkpoint; chemoattractant protein; monocyte chemoattractant ... See more keywords
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Catalpol Ameliorates Neointimal Hyperplasia in Diabetic Rats.

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Published in 2019 at "Planta medica"

DOI: 10.1055/a-0818-3689

Abstract: Catalpol, an iridoid glycoside, is an isolated natural product of Rehmannia glutinosa, which has been reported to have antidiabetic properties. This study investigated the vascular protective effects of catalpol in hyperglycemic rats with balloon-injured carotid… read more here.

Keywords: monocyte chemoattractant; chemoattractant protein; neointimal hyperplasia;
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Monocyte Chemoattractant Protein-1 as a Predictor of Coronary Atherosclerosis in Patients Receiving Coronary Angiography

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Published in 2018 at "Critical Pathways in Cardiology"

DOI: 10.1097/hpc.0000000000000140

Abstract: Background: Animal studies suggest that monocyte chemoattractant protein-1 (MCP-1) is a promising biomarker for coronary artery atherosclerosis (CAA), but human studies have been inconclusive. Objective: To determine potential relationships between plasma MCP-1 and CAA in… read more here.

Keywords: monocyte chemoattractant; obstructive caa; chemoattractant protein; angiography ... See more keywords
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Monocyte Chemoattractant Protein-1 (MCP-1) as a Potential Therapeutic Target and a Noninvasive Biomarker of Liver Fibrosis Associated With Transient Myeloproliferative Disorder in Down Syndrome.

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Published in 2017 at "Journal of Pediatric Hematology/Oncology"

DOI: 10.1097/mph.0000000000000809

Abstract: Liver fibrosis is one of the common complications of transient myeloproliferative disorder (TMD) in Down syndrome (DS), but the exact molecular pathogenesis is largely unknown. We herein report a neonate of DS with liver fibrosis… read more here.

Keywords: monocyte chemoattractant; fibrosis; liver fibrosis; chemoattractant protein ... See more keywords
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Transplantation of olfactory ensheathing cells decreases local and serological monocyte chemoattractant protein 1 level during the acute phase of rat spinal cord injury

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Published in 2022 at "NeuroReport"

DOI: 10.1097/wnr.0000000000001839

Abstract: Objectives: Monocyte chemoattractant protein 1 (MCP1) is one of the most upregulated cytokines in the spinal cord and serum throughout acute spinal cord injury (SCI). Olfactory ensheathing cells (OECs) transplantation improves SCI through multiple mechanisms,… read more here.

Keywords: cord; monocyte chemoattractant; chemoattractant protein; transplantation ... See more keywords
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Endometrial stromal cells treated by tumor necrosis factor‐α stimulate macrophages polarized toward M2 via interleukin‐6 and monocyte chemoattractant protein‐1

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Published in 2020 at "Journal of Obstetrics and Gynaecology Research"

DOI: 10.1111/jog.14135

Abstract: This study aimed to investigate the effects of endometrial stromal cells (ESC)‐derived interleukin (IL)‐6 and monocyte chemoattractant protein (MCP)‐1 on macrophage polarization in endometriosis. read more here.

Keywords: monocyte chemoattractant; chemoattractant protein; stromal cells; endometrial stromal ... See more keywords
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Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2

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Published in 2017 at "Science Signaling"

DOI: 10.1126/scisignal.aai8529

Abstract: Structure-function analysis of chemokines and their shared receptor may aid in the development of small-molecule inhibitors. Deciphering chemokine binding Chemokines are small chemoattractant proteins that bind to chemokine receptors, which are members of the family… read more here.

Keywords: monocyte chemoattractant; ccr2; receptor ccr2; chemoattractant proteins ... See more keywords
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Genetically Determined Levels of Circulating Cytokines and Risk of Stroke: Role of Monocyte Chemoattractant Protein-1

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Published in 2019 at "Circulation"

DOI: 10.1161/circulationaha.118.035905

Abstract: Background: Cytokines and growth factors have been implicated in the initiation and propagation of vascular disease. Observational studies have shown associations of their circulating levels with stroke. Our objective was to explore whether genetically determined… read more here.

Keywords: monocyte chemoattractant; risk stroke; risk; study ... See more keywords
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Predicting treatment response and clinicopathological findings in lupus nephritis with urine epidermal growth factor, monocyte chemoattractant protein-1 or their ratios

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0263778

Abstract: Introduction There is a need for sensitive and specific biomarkers to predict kidney damage and therapeutic response in lupus nephritis (LN). Monocyte chemoattractant protein-1 (MCP-1) and epidermal growth factor (EGF) are cytokines with divergent roles.… read more here.

Keywords: monocyte chemoattractant; egf; lupus nephritis; mcp ... See more keywords
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Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-α-Stimulated Adipocytes

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24010320

Abstract: As a worldwide health issue, obesity is associated with the infiltration of monocytes/macrophages into the adipose tissue causing unresolved inflammation. Monocyte chemoattractant protein-1 (MCP-1) exerts a crucial effect on obesity-related monocytes/macrophages infiltration. Clinically, aspirin and… read more here.

Keywords: chemoattractant protein; tnf; monocyte chemoattractant; stimulated adipocytes ... See more keywords