From monocyte‐derived macrophages to resident macrophages—how metabolism leads their way in cancer
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13618
Abstract: Macrophages are innate immune cells that play key roles during both homeostasis and disease. Depending on the microenvironmental cues sensed in different tissues, macrophages are known to acquire specific phenotypes and exhibit unique features that,… read more here.
Keywords: cancer; macrophages resident; way; monocyte derived ... See more keywords
Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202503480
Abstract: Obstetric antiphospholipid syndrome (OAPS) is an autoimmune disorder characterized by pathologic pregnancies and the presence of antiphospholipid antibodies (aPLs). Despite significant infiltration of decidual macrophages observed in OAPS patients, the underlying connections between decidual and… read more here.
Keywords: single cell; obstetric antiphospholipid; monocyte derived; infiltration ... See more keywords
Classical DC2 subsets and monocyte‐derived DC: Delineating the developmental and functional relationship
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Immunology"
DOI: 10.1002/eji.202149548
Abstract: To specifically tailor immune responses to a given pathogenic threat, dendritic cells (DC) are highly heterogeneous and comprise many specialized subtypes, including conventional DC (cDC) and monocyte‐derived DC (MoDC), each with distinct developmental and functional… read more here.
Keywords: developmental functional; functional relationship; immune responses; cdc2 ... See more keywords
Distinct spatiotemporal features of microglia and monocyte‐derived macrophages in glioma
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Immunology"
DOI: 10.1002/eji.202250161
Abstract: Gliomas are the most frequent primary tumors of the brain. Glioma progression is regulated by the tumor microenvironment, which is mainly composed of tumor‐associated microglia (TA‐MG) and monocyte‐derived macrophages (MDM). Recent studies have highlighted the… read more here.
Keywords: spatiotemporal features; derived macrophages; progression; monocyte derived ... See more keywords
Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte‐derived cells does not alter the induction or progression of hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34505
Abstract: Due to a combination of rapid disease progression and the lack of curative treatment options, hepatocellular carcinoma (HCC) is one of the deadliest cancers worldwide. Infiltrated, monocyte‐derived, tumor‐associated macrophages are known to play a role… read more here.
Keywords: hepatocellular carcinoma; progression; depletion; monocyte derived ... See more keywords
The SC cell line as an in vitro model of human monocytes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of leukocyte biology"
DOI: 10.1002/jlb.1a1221-680r
Abstract: In vitro analysis of human macrophages is generally hampered by the necessity to differentiate them from peripheral blood monocytes. We have analyzed to which extent noncancerous SC monocytes could be used as an in vitro… read more here.
Keywords: expression; cell line; monocyte derived; derived macrophages ... See more keywords
Highly restricted SARS‐CoV‐2 receptor expression and resistance to infection by primary human monocytes and monocyte‐derived macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4cova1121-579rr
Abstract: Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS‐CoV2), which causes the disease COVID‐19, has caused an unprecedented global pandemic. Angiotensin‐converting enzyme 2 (ACE2) is the major cellular receptor for SARS‐CoV2 entry, which is facilitated by… read more here.
Keywords: sars cov2; derived macrophages; infection; monocyte derived ... See more keywords
Kupffer Cell and Monocyte-Derived Macrophage Identification by Immunofluorescence on Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse Liver Sections.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0704-6_6
Abstract: Kupffer cells are the liver-resident macrophages and represent the first line of defense between the pathogens circulating from the intestines through the portal vein and systemic circulation. Recent works have highlighted the complex heterogeneity of… read more here.
Keywords: fixed paraffin; paraffin embedded; formalin fixed; macrophage ... See more keywords
Use of Human Monocyte-Derived Macrophages to Study Neisseria gonorrhoeae Infection.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9496-0_18
Abstract: Macrophages are critical cells in the innate immune response to microorganisms sensed in the tissues. During infections, the interaction between pathogens and macrophages leads to a macrophage response that includes cytokine production, antigen processing and… read more here.
Keywords: response; infection; human monocyte; neisseria gonorrhoeae ... See more keywords
Experimental hypercoagulable state induced by tissue factor expression in monocyte-derived dendritic cells and its modulation by C1 inhibitor
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-018-1688-0
Abstract: The crosstalk between immune and coagulation systems plays pivotal roles in host defense, which may involve monocyte-derived dendritic cells (moDCs). Our objectives were to elucidate the role of moDCs in coagulation under inflammatory conditions and… read more here.
Keywords: modcs; hypercoagulable state; derived dendritic; expression ... See more keywords
"Monocytes in B-Cell Malignancies: Their Role in Disease Progression and Therapy Resistance".
Sign Up to like & getrecommendations! Published in 2025 at "Current oncology reports"
DOI: 10.1007/s11912-025-01732-9
Abstract: Although current treatments have improved outcomes in B-cell malignancies, therapy resistance remains a major challenge and is often driven by the tumor microenvironment. The purpose of this review was to assess the roles of monocytes… read more here.
Keywords: monocyte derived; therapy resistance; monocytes cell; cell malignancies ... See more keywords