Articles with "monocyte infiltration" as a keyword



Hypoxia-induced miR-210-3p expression in lung adenocarcinoma potentiates tumor development by regulating CCL2-mediated monocyte infiltration.

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Published in 2022 at "Molecular oncology"

DOI: 10.1002/1878-0261.13260

Abstract: In most cancers, tumor hypoxia downregulates the expression of C-C motif chemokine 2 (CCL2), and this downregulation has been implicated in monocyte infiltration and tumor progression; however, the molecular mechanism is yet not clear. We… read more here.

Keywords: mir 210; lung adenocarcinoma; ccl2; expression ... See more keywords

Endothelial HSPA12B regulates myocardial monocyte infiltration and inflammatory activity after myocardial infarction

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Published in 2025 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2025.1587898

Abstract: Introduction Cardiac macrophages are essential mediators of inflammation and tissue remodeling following myocardial infarction (MI). Endothelial cell-specific heat shock protein A12B (eHSPA12B) has emerged as a key vascular regulator, but its role in modulating immune… read more here.

Keywords: hspa12b; monocyte infiltration; myocardial infarction; infiltration ... See more keywords

Fucoidan from Fucus vesiculosus alleviates MetALD via promoting HIF-1α ubiquitination to suppress peripheral monocyte infiltration

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Published in 2025 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2025.1617175

Abstract: Metabolic and alcohol-related liver disease (MetALD), characterized by excessive alcohol intake in individuals with metabolic dysfunction, is a growing health burden worldwide. Hepatic macrophages play a pivotal role in MetALD pathogenesis, with pro-inflammatory infiltrating monocytes/macrophages… read more here.

Keywords: monocyte; monocyte infiltration; peripheral monocyte; fucoidan ... See more keywords

CXCL16 Promotes Ly6Chigh Monocyte Infiltration and Impairs Heart Function after Acute Myocardial Infarction.

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Published in 2023 at "Journal of immunology"

DOI: 10.4049/jimmunol.2200249

Abstract: High CXCL16 levels during acute cardiovascular events increase long-term mortality. However, the mechanistic role of CXCL16 in myocardial infarction (MI) is unknown. Here we investigated the role of CXCL16 in mice with MI injury. CXCL16… read more here.

Keywords: ly6chigh monocyte; function; cxcl16; monocyte infiltration ... See more keywords