A monocyte-keratinocyte-derived co-culture assay accurately identifies efficacies of BET inhibitors as therapeutic candidates for psoriasiform dermatitis.
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DOI: 10.1016/j.jdermsci.2020.08.005
Abstract: BACKGROUND Bromodomain and extra-terminal (BET) proteins perform key roles in epigenetic control of gene expression that is involved in inflammatory conditions, including psoriasiform dermatitis (PsD). Predicting which (of many potential available BET inhibitors) will be… read more here.
Keywords: psoriasiform dermatitis; bet; bet inhibitors; monocyte keratinocyte ... See more keywords