Cysteine-Containing Peptides Stimulate Monocyte Migration through NADPH-Oxidase Activation
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3766-2
Abstract: We analyzed migration of monocytes under the effect of apocinin (NADPH inhibitor) and PD98059 (blocker of extracellular MEK/ERK kinase involved in Nox4 oxidase-mediated migration of monocytes). Migration of monocytes stimulated by cysteine-containing peptides (fragments of… read more here.
Keywords: oxidase; migration; containing peptides; monocyte migration ... See more keywords
PCSK9 regulates the chemokine receptor CCR2 on monocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.02.085
Abstract: Monocyte migration is a key element in atherosclerosis. LDL-C facilitates monocyte migration via induction of CCR2. PCSK9 regulates cell surface expression of the LDL-R and is expressed in vascular smooth muscle cells (VSMCs). The present… read more here.
Keywords: pcsk9 regulates; ccr2; ldl; expression ... See more keywords
Atorvastatin Inhibits Endothelial PAI-1-Mediated Monocyte Migration and Alleviates Radiation-Induced Enteropathy
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DOI: 10.3390/ijms22041828
Abstract: Intestinal injury is observed in cancer patients after radiotherapy and in individuals exposed to radiation after a nuclear accident. Radiation disrupts normal vascular homeostasis in the gastrointestinal system by inducing endothelial damage and senescence. Despite… read more here.
Keywords: pai; radiation induced; induced enteropathy; atorvastatin ... See more keywords
Nesfatin-1 Stimulates CCL2-dependent Monocyte Migration And M1 Macrophage Polarization: Implications For Rheumatoid Arthritis Therapy
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DOI: 10.7150/ijbs.77987
Abstract: Rheumatoid arthritis (RA) is a prototypic inflammatory disease, characterized by the infiltration of proinflammatory cytokines into the joint synovium and the migration of mononuclear cells into inflammatory sites. The adipokine nesfatin-1 is linked to inflammatory… read more here.
Keywords: monocyte migration; rheumatoid arthritis; expression; nesfatin ... See more keywords