Cysteine-Containing Peptides Stimulate Monocyte Migration through NADPH-Oxidase Activation
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3766-2
Abstract: We analyzed migration of monocytes under the effect of apocinin (NADPH inhibitor) and PD98059 (blocker of extracellular MEK/ERK kinase involved in Nox4 oxidase-mediated migration of monocytes). Migration of monocytes stimulated by cysteine-containing peptides (fragments of… read more here.
Keywords: oxidase; migration; containing peptides; monocyte migration ... See more keywords
MOSPD2 regulates the activation state of αLβ2 integrin to control monocyte migration: applicability for treatment of chronic inflammatory diseases
Sign Up to like & getrecommendations! Published in 2025 at "Immunologic Research"
DOI: 10.1007/s12026-025-09633-6
Abstract: Monocytes are innate immune cells that drive the chronicity of various inflammatory diseases. Monocyte migration to inflamed tissues involves multiple steps of interaction with the vascular endothelium and the extracellular matrix (ECM), a process mediated… read more here.
Keywords: monocyte migration; migration; adhesion; chronic inflammatory ... See more keywords
PCSK9 regulates the chemokine receptor CCR2 on monocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.02.085
Abstract: Monocyte migration is a key element in atherosclerosis. LDL-C facilitates monocyte migration via induction of CCR2. PCSK9 regulates cell surface expression of the LDL-R and is expressed in vascular smooth muscle cells (VSMCs). The present… read more here.
Keywords: pcsk9 regulates; ccr2; ldl; expression ... See more keywords
The MiR-139-5p and CXCR4 axis may play a role in high glucose-induced inflammation by regulating monocyte migration
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DOI: 10.1038/s41598-025-91100-1
Abstract: MicroRNAs, a class of small non-coding RNA molecules that regulate gene expression post-transcriptionally, are implicated in various pathological conditions including diabetes mellitus (DM). DM has been increasingly recognized as an inflammatory disease and monocytes play… read more here.
Keywords: high glucose; monocyte migration; mir 139; glucose ... See more keywords
Atorvastatin Inhibits Endothelial PAI-1-Mediated Monocyte Migration and Alleviates Radiation-Induced Enteropathy
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DOI: 10.3390/ijms22041828
Abstract: Intestinal injury is observed in cancer patients after radiotherapy and in individuals exposed to radiation after a nuclear accident. Radiation disrupts normal vascular homeostasis in the gastrointestinal system by inducing endothelial damage and senescence. Despite… read more here.
Keywords: pai; radiation induced; induced enteropathy; atorvastatin ... See more keywords
Nesfatin-1 Stimulates CCL2-dependent Monocyte Migration And M1 Macrophage Polarization: Implications For Rheumatoid Arthritis Therapy
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DOI: 10.7150/ijbs.77987
Abstract: Rheumatoid arthritis (RA) is a prototypic inflammatory disease, characterized by the infiltration of proinflammatory cytokines into the joint synovium and the migration of mononuclear cells into inflammatory sites. The adipokine nesfatin-1 is linked to inflammatory… read more here.
Keywords: monocyte migration; rheumatoid arthritis; expression; nesfatin ... See more keywords