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Monocyte NLRP3-IL-1β Hyperactivation Mediates Neuronal and Synaptic Dysfunction in Perioperative Neurocognitive Disorder.

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Published in 2022 at "Advanced science"

DOI: 10.1002/advs.202104106

Abstract: Perioperative neurocognitive disorder may develop in vulnerable patients following major operation. While neuroinflammation is linked to the cognitive effects of surgery, how surgery and immune signaling modulate neuronal circuits, leading to learning and memory impairment… read more here.

Keywords: surgery; perioperative neurocognitive; neurocognitive disorder; neuronal synaptic ... See more keywords