Multiplexed Label-Free Fractionation of Peripheral Blood Mononuclear Cells for Identification of Monocyte-Platelet Aggregates.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b04415
Abstract: Monocytes and platelets play key roles in atherosclerosis and thrombosis, and circulating monocyte-platelet aggregates (MPA) in blood have been widely proposed as surrogate biomarkers for cardiovascular risk stratification and monitoring antiplatelet therapies. However, conventional MPA… read more here.
Keywords: fractionation; monocyte platelet; blood; platelet aggregates ... See more keywords
Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2021.1900159
Abstract: Abstract Acute Coronary Syndromes (ACS) with plaque erosion display dysregulated hyaluronan metabolism, with increased hyaluronidase-2 (HYAL2) expression. However, the expression and the role of this enzyme on platelets has never been explored. We evaluated the… read more here.
Keywords: hyaluronidase; monocyte platelet; acute coronary; coronary syndromes ... See more keywords
Impact of Mon2 monocyte‐platelet aggregates on human coronary artery disease
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DOI: 10.1111/eci.12911
Abstract: Monocyte‐platelet aggregates (MPAs) form when Mon1, Mon2 or Mon3 monocyte subsets adhere to platelets. They are pathophysiologically linked to coronary artery disease (CAD). However, their individual roles in the occurrence of diffuse CAD remain unknown. read more here.
Keywords: mon2; coronary artery; monocyte platelet; platelet aggregates ... See more keywords
Regulation of Atherosclerosis by Toll-Like Receptor 4 Induced by Serum Amyloid 1: A Systematic In Vitro Study
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DOI: 10.1155/2022/4887593
Abstract: The objective of this study was to investigate the effects of serum amyloid 1 (SAA1) on activation of endothelial cells, formation of foam cells, platelet aggregation, and monocyte/platelet adhesion to endothelial cells. The effect of… read more here.
Keywords: endothelial cells; platelet adhesion; monocyte platelet; platelet ... See more keywords
Influence of chronic hepatitis C infection on the monocyte-to-platelet ratio: data analysis from the National Health and Nutrition Examination Survey (2009–2016)
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DOI: 10.1186/s12889-021-11267-w
Abstract: Hepatitis C virus (HCV) causes life-threatening chronic infections. Implementation of novel, economical or widely available screening tools can help detect unidentified cases and facilitate their linkage to care. We investigated the relationship between chronic HCV… read more here.
Keywords: monocyte platelet; infection; hcv; platelet ratio ... See more keywords