Abstract 6181: Dynamic changes in monocyte and reticulocyte counts predict mechanism-based anemia development and recovery during ATR inhibitor treatment in phase I/II trials
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DOI: 10.1158/1538-7445.am2023-6181
Abstract: Introduction: Clinical trials are exploring ATR inhibitors (ATRi) in genomically selected contexts. However, dose-dependent anemia has limited the therapeutic index of this class. We hypothesized that monocytes and reticulocytes are more vulnerable to ATRi due… read more here.
Keywords: index; monocyte reticulocyte; reticulocyte; time ... See more keywords