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Published in 2020 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23576
Abstract: Chronic myelomonocytic leukemia (CMML) is characterized by persistent monocytosis and dysplastic features of blood cells. No specific genetic abnormalities are present in CMML, and reactive monocytosis should be excluded. An increase in classical monocytes (MO1)…
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Keywords:
monocytosis;
monocyte subsets;
chronic myelomonocytic;
reactive monocytosis ... See more keywords
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Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108683
Abstract: Monocytes are a versatile and dynamic population, but its implication in Behçet's Disease (BD) remains elusive. We investigated the proportion, phenotypical and functional alterations in classical monocytes (CM), intermediate monocytes (IM) and non-classical monocytes (NCM)…
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Keywords:
subsets patients;
patients beh;
aberrant monocyte;
disease ... See more keywords
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Published in 2021 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2021.02.005
Abstract: BACKGROUND Proprotein convertase subtilisin/kexin type-9 (PCSK9) is an enzyme promoting the degradation of low-density lipoprotein receptors (LDL-R) in hepatocytes. Inhibition of PCSK9 has emerged as a novel target for lipid-lowering therapy. Monocytes are crucially involved…
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Keywords:
proprotein convertase;
disease;
monocyte subsets;
pcsk9 levels ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52579-7
Abstract: Monocytes are plastic heterogeneous immune cells involved in host-parasite interactions critical for malaria pathogenesis. Human monocytes have been subdivided into three populations based on surface expression of CD14 and CD16. We hypothesised that proportions and…
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Keywords:
anaemia cerebral;
severe malarial;
malarial anaemia;
monocyte subsets ... See more keywords
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Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0196
Abstract: Monocytes are one of the principal immune defense cells that encounter infectious agents. However, an essential role of monocytes has been shown in the spread of viruses throughout the human body. Considering this dilemma, this…
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Keywords:
hla expressions;
disease severity;
monocyte subsets;
covid cases ... See more keywords
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Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac133
Abstract: OBJECTIVE Hospital-acquired pneumonia (HAP) is one of the most common diseases in the intensive care unit, where the development of disease is closely related with the host immune response. Monocytes play an important role in…
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Keywords:
monocyte subsets;
newly emerged;
circulating monocyte;
hospital acquired ... See more keywords
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Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15791
Abstract: Sepsis is characterized by dynamic changes of the immune system resulting in deregulated inflammation and failure of homoeostasis and can escalate to septic shock. Circulating monocytes and other innate immune cells are among the first…
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Keywords:
septic shock;
monocyte subsets;
patients septic;
short term ... See more keywords
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Published in 2018 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.13770
Abstract: Monocytes are likely to play a significant role in the pathogenesis of preeclampsia (PE) and intrauterine fetal growth restriction (IUGR), given their role in homeostasis and tissue repair. Our aim was to study the gestational…
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Keywords:
growth restriction;
preeclampsia intrauterine;
intrauterine fetal;
monocyte subsets ... See more keywords
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Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00773-20
Abstract: The activation phenotypes and functional changes in monocyte subsets during hepatitis C virus (HCV) elimination in HIV/HCV-coinfected patients were evaluated. Twenty-two HIV/HCV-coinfected patients on suppressive combination antiretroviral treatment (cART) achieving HCV elimination after direct-acting antiviral…
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Keywords:
activation;
monocyte subsets;
hiv;
treatment ... See more keywords
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Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.2641
Abstract: Background monocytes are largely recognized as drivers of the atherosclerosis development, the leading determinant of cardiovascular (CV) morbidity in rheumatoid arthritis (RA). Far from being a unique population, functionally and phenotypically subpopulations can be distinguished,…
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Keywords:
ace expression;
monocyte subsets;
cd16;
expression associated ... See more keywords
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Published in 2019 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.118.311022
Abstract: Objective— Three distinct human monocyte subsets have been identified based on the surface marker expression of CD14 and CD16. We hypothesized that monocytes were likely more heterogeneous in composition. Approach and Results— We used the…
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Keywords:
monocyte subsets;
mass cytometry;
monocyte heterogeneity;
cad ... See more keywords