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Monocytes Elicit a Neutrophil-Independent Th1/Th17 Response Upon Immunization With a Mincle-Dependent Glycolipid Adjuvant

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.880474

Abstract: Successful subunit vaccination with recombinant proteins requires adjuvants. The glycolipid trehalose-dibehenate (TDB), a synthetic analog of the mycobacterial cord factor, potently induces Th1 and Th17 immune responses and is a candidate adjuvant for human immunization.… read more here.

Keywords: immunization; monocytes elicit; th17; mincle ... See more keywords