A Zinc‐ and Calcium‐Rich Lysosomal Nanoreactor Rescues Monocyte/Macrophage Dysfunction under Sepsis
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205097
Abstract: Sepsis is a dysregulation of the immune response to pathogens and has high morbidity and mortality worldwide. However, the unclear mapping and course of dysregulated immune cells currently hinders the development of advanced therapeutic strategies… read more here.
Keywords: sepsis; monocyte macrophage; calcium; zinc ... See more keywords
Pleural CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250019
Abstract: Nowadays laparoscopic interventions enable the collection of resident macrophage populations out of the human cavities. We employed this technique to isolate pleural monocytes/macrophages from healthy young adults who underwent a correction of pectus excavatum. High… read more here.
Keywords: macrophages healthy; cd14 monocytes; monocytes macrophages; high expression ... See more keywords
Dielectrophoretic characterization and separation of monocytes and macrophages using 3D carbon‐electrodes
Sign Up to like & getrecommendations! Published in 2019 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201800324
Abstract: Monocyte heterogeneity and its prevalence are revealed as indicator of several human diseases ranking from cardiovascular diseases to rheumatoid arthritis, chronic kidney diseases, autoimmune multiple sclerosis, and stroke injuries. When monocytes and macrophages are characterized… read more here.
Keywords: monocytes macrophages; carbon; carbon electrodes; using carbon ... See more keywords
The effects of sulfated hyaluronan in breast, lung and colorectal carcinoma and monocytes/macrophages cells: Its role in angiogenesis and tumor progression.
Sign Up to like & getrecommendations! Published in 2022 at "IUBMB life"
DOI: 10.1002/iub.2604
Abstract: Hyaluronan (HA) is a component of the extracellular matrix (ECM) it is the main non-sulfated glycosaminoglycan able to modulate cell behavior in the healthy and tumor context. Sulfated hyaluronan (sHA) is a biomaterial derived from… read more here.
Keywords: tumor; lung colorectal; monocytes macrophages; sulfated hyaluronan ... See more keywords
Isolation and Analysis of Human Monocytes and Adipose Tissue Macrophages.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9130-3_3
Abstract: Monocytes and macrophages are cells of the innate immune system, existing in circulation and permeating every tissue of the human body. These cells represent the first responders to stress, and their inflammatory activation forms part… read more here.
Keywords: monocytes macrophages; tissue macrophages; isolation analysis; tissue ... See more keywords
Model-Based Assessment of the Contribution of Monocytes and Macrophages to the Pharmacokinetics of Monoclonal Antibodies.
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical research"
DOI: 10.1007/s11095-022-03177-2
Abstract: PURPOSE We have hypothesized that a high concentration of circulating monocytes and macrophages may contribute to the fast weight-based clearance of monoclonal antibodies (mAbs) in young children. Exploring this hypothesis, this work uses modeling to… read more here.
Keywords: model based; circulating monocytes; monocytes macrophages; based assessment ... See more keywords
The role of monocytes/macrophages in Leishmania infection: a glance at the human response.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105456
Abstract: Leishmania are obligate intracellular parasites of mononuclear phagocytes transmitted by Phlebotomine sandflies. Monocytes are one of the main cell types recruited to the site of the bite having an important role in the defense against Leishmania… read more here.
Keywords: monocytes macrophages; macrophages leishmania; infection; role monocytes ... See more keywords
Monocytes and Macrophages in Heart Valves: Uninvited Guests or Critical Performers?
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in biomedical engineering"
DOI: 10.1016/j.cobme.2018.02.003
Abstract: Monocytes and macrophages are critical components of the myeloid niche of the innate immune system. In addition to traditional roles as phagocytes, this subsection of innate immunity has been implicated in its ability to regulate… read more here.
Keywords: monocytes macrophages; macrophages heart; uninvited guests; valves uninvited ... See more keywords
PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental hematology"
DOI: 10.1016/j.exphem.2017.08.002
Abstract: Monocytes/macrophages differentiating from bone marrow (BM) cells pulsed for 2 hours at 37°C with a stabilized derivative of prostaglandin E2, 16,16-dimethyl PGE2 (dmPGE2), migrated less efficiently toward a chemoattractant than monocytes/macrophages differentiated from BM cells… read more here.
Keywords: monocytes macrophages; migration daughter; vitro vivo; marrow ... See more keywords
Regulation of immunophenotype modulation of monocytes-macrophages from M1 into M2 by prostate cancer cell-culture supernatant via transcription factor STAT3.
Sign Up to like & getrecommendations! Published in 2018 at "Immunology letters"
DOI: 10.1016/j.imlet.2018.02.009
Abstract: BACKGROUND Transcription factor STAT3 has a prominent innate immunity effect on cancer progression. We determined the regulation of STAT3 in the immunophenotype modulation of macrophages from M1 into M2 induced by the cell-culture supernatant of… read more here.
Keywords: monocytes macrophages; prostate cancer; transcription factor; factor stat3 ... See more keywords
Increased Tim-3+ monocytes/macrophages are associated with disease severity in patients with IgA nephropathy.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107666
Abstract: T-cell immunoglobulin and mucin-domain-containing protein-3 (Tim-3) plays multiple important roles in immune response and participates in the pathogenesis of various inflammatory diseases by regulating macrophage polarization. However, its functions in the development of IgA nephropathy… read more here.
Keywords: monocytes macrophages; iga nephropathy; cd14 tim; tim ... See more keywords