Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes
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DOI: 10.1126/scisignal.aan2392
Abstract: Age-related reduction of the adaptor protein TRAF3 compromises the innate immune response of monocytes from older individuals. Aging compromises innate immunity Older adults are more susceptible than younger adults to death resulting from influenza A… read more here.
Keywords: rig; iav; monocytes older; older individuals ... See more keywords