122. Silibinin regulates the NF-κB pathway and NLRP1/NLRP3 inflammasomes induced by monosodium urate in monocytes from preeclamptic women and THP-1 cells
Sign Up to like & getrecommendations! Published in 2018 at "Pregnancy Hypertension"
DOI: 10.1016/j.preghy.2018.08.237
Abstract: Introduction Preeclampsia (PE) is characterized by a state of abnormal activation of the innate immune system. It’s associated with hyperuricemia and elevated serum levels of inflammatory cytokines. Uric acid crystals can activate inflammasome, a multiprotein… read more here.
Keywords: preeclamptic women; inflammatory cytokines; nlrp1 nlrp3; silibinin ... See more keywords