CD300f epitopes are specific targets for acute myeloid leukemia with monocytic differentiation
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DOI: 10.1002/1878-0261.12549
Abstract: Antibody‐based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs). Achieving greater success with therapeutic antibodies requires careful characterization of… read more here.
Keywords: myeloid leukemia; monocytic differentiation; cd300f; acute myeloid ... See more keywords
Opposing roles of ICAT and Wnt/β-catenin signaling in NSC67657-induced monocytic differentiation
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DOI: 10.18632/oncotarget.19457
Abstract: NSC67657 is a new steroid drug that induces monocytic differentiation of acute myeloid leukemia cells. Here, we demonstrate that NSC67657 has opposing effects on expression of downstream targets of inhibitor of β-catenin and TCF (ICAT)… read more here.
Keywords: catenin signaling; nsc67657 induced; icat wnt; monocytic differentiation ... See more keywords