Priming with GM-CSF instead of G-CSF enhances CAG-induced apoptosis of acute monocytic leukemia cells in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03857-8
Abstract: High expression of granulocyte–macrophage colony-stimulating factor (GM-CSF) receptor has been found in myelomonocytic or monocytic subtypes (M4/M5) of acute myeloid leukemia. Herein, we aimed to improve the effect of CAG [Ara-C, ACR, and G-CSF (granulocyte… read more here.
Keywords: cag; acute monocytic; monocytic leukemia; csf ... See more keywords
PFKFB4 is critical for the survival of acute monocytic leukemia cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.174
Abstract: Acute myeloid leukemia (AML), which is characterized by an overproliferation of blood cells, is divided into several subtypes in adults and children. Of those subtypes, acute monocytic leukemia (M4/M5, AMoL) is reported to be associated… read more here.
Keywords: acute monocytic; amol; pfkfb4 critical; monocytic leukemia ... See more keywords
Characterization of an acquired jumping translocation involving 3q13.31-qter in a patient with de novo acute monocytic leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2017.06.002
Abstract: We studied an adult with de novo acute monocytic leukemia and a dismal outcome where her leukemic cells harbored an acquired rare jumping translocation (JT). We used oligo-based array CGH (oaCGH) analysis, fluorescence in situ… read more here.
Keywords: acute monocytic; novo acute; monocytic leukemia; involving 3q13 ... See more keywords
CRISPR-Cas9 Editing of Human Histone Deubiquitinase Gene USP16 in Human Monocytic Leukemia Cell Line THP-1
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.679544
Abstract: USP16 is a histone deubiquitinase which facilitates G2/M transition during the cell cycle, regulates DNA damage repair and contributes to inducible gene expression. We mutated the USP16 gene in a high differentiation clone of the… read more here.
Keywords: line; monocytic leukemia; differentiation; histone deubiquitinase ... See more keywords
Isofraxidin enhances hyperthermia‑induced apoptosis via redox modification in acute monocytic leukemia U937 cells.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular medicine reports"
DOI: 10.3892/mmr.2023.12928
Abstract: The cell‑killing potential of most chemotherapeutic agents is enhanced by a temperature elevation. Isofraxidin (IF) is a coumarin compound widely found in plants, such as the Umbelliferae or Chloranthaceae families. IF induces anticancer effects in… read more here.
Keywords: leukemia u937; apoptosis; monocytic leukemia; acute monocytic ... See more keywords