Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer’s Disease
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DOI: 10.1016/j.celrep.2018.11.095
Abstract: Abnormalities of the endolysosomal and autophagy systems are found in Alzheimer's disease, but it is not clear whether defects in these systems are a cause or consequence of degenerative processes in the disease. In human… read more here.
Keywords: monogenic alzheimer; alzheimer disease; app; processing app ... See more keywords