Articles with "monogenic paradigms" as a keyword



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The evolution of gene‐guided management of inherited arrhythmia syndromes: Peering beyond monogenic paradigms towards comprehensive genomic risk scores

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Published in 2020 at "Journal of Cardiovascular Electrophysiology"

DOI: 10.1111/jce.14415

Abstract: Inherited arrhythmia syndromes have traditionally been viewed as monogenic forms of disease whose pathophysiology is driven by a single highly penetrant rare genetic variant. Although an accurate depiction of a proportion of genetic variants, the… read more here.

Keywords: arrhythmia syndromes; risk; inherited arrhythmia; monogenic paradigms ... See more keywords