Monogenic, polygenic, and oligogenic familial hypercholesterolemia
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Lipidology"
DOI: 10.1097/mol.0000000000000609
Abstract: Purpose of reviewFamilial hypercholesterolemia has long been considered a monogenic disorder. However, recent advances in genetic analyses have revealed various forms of this disorder, including polygenic and oligogenic familial hypercholesterolemia. We review the current understanding… read more here.
Keywords: familial hypercholesterolemia; oligogenic familial; hypercholesterolemia; monogenic polygenic ... See more keywords
Autoantibody repertoire characterization provides insight into the pathogenesis of monogenic and polygenic autoimmune diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1106537
Abstract: Autoimmune diseases vary in the magnitude and diversity of autoantibody profiles, and these differences may be a consequence of different types of breaks in tolerance. Here, we compared the disparate autoimmune diseases autoimmune polyendocrinopathy–candidiasis–ecto-dermal dystrophy… read more here.
Keywords: cell; autoimmune diseases; autoimmune; monogenic polygenic ... See more keywords