Selective Removal of Unhydrolyzed Monolinked Peptides from Enriched Crosslinked Peptides To Improve the Coverage of Protein Complex Analysis.
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DOI: 10.1021/acs.analchem.1c04927
Abstract: Chemical crosslinking combined with mass spectrometry (CXMS) has allowed the global characterization of protein complexes with high throughput and accuracy. Although enrichable crosslinkers have been introduced to exclude the interference of regular peptides, the crosslinked… read more here.
Keywords: protein complex; chemistry; complex analysis; monolinked peptides ... See more keywords