Targeted Chemoradiotherapy of Prostate Cancer Using Gold Nanoclusters with Protease Activatable Monomethyl Auristatin E.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c23780
Abstract: Combined radiotherapy (RT) and chemotherapy are prescribed to patients with advanced prostate cancer (PCa) to increase their survival; however, radiation-related side effects and systematic toxicity caused by chemotherapeutic drugs are unavoidable. To improve the precision… read more here.
Keywords: cancer; chemotherapy; gold; monomethyl auristatin ... See more keywords
Non-toxic fragment of botulinum neurotoxin type A and monomethyl auristatin E conjugate for targeted therapy for neuroendocrine tumors
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Gene Therapy"
DOI: 10.1038/s41417-020-0167-x
Abstract: Surgical resection is the only cure for neuroendocrine tumors (NETs). However, widespread metastases have already occured by the time of initial diagnosis in many cases making complete surgical removal impossible. We developed a recombinant heavy-chain… read more here.
Keywords: botulinum neurotoxin; rhcr; neuroendocrine tumors; monomethyl auristatin ... See more keywords