Abstract 148: Neonatal Mouse Heart Regeneration is Dependent on Mononuclear Diploid Cardiomyocytes and Paracrine IGF2 Signaling
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.148
Abstract: In normal mice, injury to the newborn heart is efficiently regenerated, but this capacity is lost by one week after birth when most cardiomyocytes have become post-mitotic. Concurrently during the first week, most cardiomyocytes become… read more here.
Keywords: heart; mononuclear diploid; regeneration; diploid cardiomyocytes ... See more keywords
Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008354
Abstract: Recent evidence implicates mononuclear diploid cardiomyocytes as a proliferative and regenerative subpopulation of the postnatal heart. The number of these cardiomyocytes is a complex trait showing substantial natural variation among inbred mouse strains based on… read more here.
Keywords: kinase; tnni3k; diploid cardiomyocyte; mononuclear diploid ... See more keywords