Engineered Bacterial Flavin‐Dependent Monooxygenases for the Regiospecific Hydroxylation of Polycyclic Phenols
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DOI: 10.1002/cbic.202100480
Abstract: 4‐Hydroxyphenylacetate 3‐hydroxylase (4HPA3H), a flavin‐dependent monooxygenase from E. coli that catalyzes the hydroxylation of monophenols to catechols, was modified by rational redesign to convert also more bulky substrates, especially phenolic natural products like phenylpropanoids, flavones… read more here.
Keywords: flavin dependent; monooxygenases regiospecific; bacterial flavin; dependent monooxygenases ... See more keywords