Enzymatic Synthesis of the Unnatural Nucleotide 2’‐Deoxyisoguanosine 5’‐Monophosphate
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200295
Abstract: Naturally occurring DNA contains four canonical bases, forming two Watson‐Crick base pairs (adenine‐thymine, guanine‐cytosine). Efforts over the past decades have led to the development of several unnatural base pairs, enabling the synthesis of unnatural DNA… read more here.
Keywords: monophosphate; deoxyisoguanosine monophosphate; synthesis unnatural; unnatural dna ... See more keywords
Cilostamide, a phosphodiesterase 3A inhibitor, sustains meiotic arrest of rat oocytes by modulating cyclic adenosine monophosphate level and the key regulators of maturation promoting factor
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30328
Abstract: Cilostamide, a phosphodiesterase 3A (Pde3A) inhibitor, is known to increase intraoocyte cyclic adenosine monophosphate (cAMP) level which is involved in sustaining meiotic arrest of the oocytes. To explore the mechanisms involved in the cilostamide‐mediated meiotic… read more here.
Keywords: meiotic arrest; arrest; monophosphate; cilostamide phosphodiesterase ... See more keywords
The Chemistry of the Noncanonical Cyclic Dinucleotide 2'3'-cGAMP and Its Analogs.
Sign Up to like & getrecommendations! Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2015_43
Abstract: The cyclic dinucleotides (CDNs) cyclic diguanosine monophosphate (c-diGMP) and cyclic diadenosine monophosphate (c-diAMP) with two canonical 3'→5' internucleotide linkages are ubiquitous second messenger molecules in bacteria, regulating a multitude of physiological processes. Recently the noncanonical… read more here.
Keywords: chemistry noncanonical; noncanonical cyclic; chemistry; cgamp ... See more keywords
Comprehensive characterization of Guanosine monophosphate synthetase in Nicotiana tabacum.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06718-x
Abstract: BACKGROUND Guanosine monophosphate (GMP) synthetase is an enzyme that converts xanthosine monophosphate to GMP. GMP plays an essential role in plant development and responses to internal and external stimuli. It also plays a crucial role… read more here.
Keywords: tobacco; synthase; gmp; gmp synthase ... See more keywords
Amplification of Chirality by Adenosine Monophosphate-Capped Luminescent Gold Nanoclusters in Nematic Lyotropic Chromonic Liquid Crystal Tactoids
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DOI: 10.1021/acsomega.8b03335
Abstract: Amplification of chirality across length scales is a key concept pertinent to many models aiming to unravel the origin of homochirality. Tactoids of lyotropic chromonic liquid crystals formed by DNA, dyes, and other flat ionic… read more here.
Keywords: adenosine monophosphate; amplification chirality; monophosphate; gold ... See more keywords
Elongation factor P modulates Acinetobacter baumannii physiology and virulence as a cyclic dimeric guanosine monophosphate effector
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209838119
Abstract: Significance Many bacteria use the second messenger cyclic diguanosine monophosphate (c-di-GMP) to control diverse biological functions. Here, we show that A1S_2419, an elongation factor P (EF-P) from the human pathogenic bacterium Acinetobacter baumannii, is a… read more here.
Keywords: monophosphate; physiology; acinetobacter baumannii; elongation factor ... See more keywords
Recognition of tRNAHis in an RNase P-Free Nanoarchaeum
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DOI: 10.1128/spectrum.04621-22
Abstract: Mature tRNAHis has, at its 5′-terminus, an extra guanosine with 5′-monophosphate, designated G-1. G-1 is the major recognition element for histidyl-tRNA synthetase (HisRS), regardless of whether it is of eukaryotic or prokaryotic origin. ABSTRACT The… read more here.
Keywords: recognition; trnahis; monophosphate; nanoarchaeum ... See more keywords
Nutritional value of black soldier fly (Hermetia illucens) larvae processed by different methods
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DOI: 10.1371/journal.pone.0263924
Abstract: Nutritional value of black soldier fly (Hermetia illucens) larvae (BSFL) processed by three different methods of treatment was compared. The resulting products were the spray-dried BSFL (SPR), oven-dried BSFL 1 (OVN1) and oven-dried BSFL 2… read more here.
Keywords: monophosphate; nutritional value; soldier fly; black soldier ... See more keywords
Effective and repeatable chromatographic separation of 5 nucleotides in infant formula milk powder by ion-pair high-performance liquid chromatography-ultraviolet.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dairy science"
DOI: 10.3168/jds.2021-21133
Abstract: A robust method using HPLC-UV was developed to improve the accuracy and repeatability of a quantitative method to detect 5 nucleotides (cytidine-monophosphate, uridine monophosphate, adenosine monophosphate, guanine monophosphate, and inosine monophosphate) in infant formulas. The… read more here.
Keywords: formula milk; monophosphate; milk powder; milk ... See more keywords
Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.637399
Abstract: Innate immune pathways are the first line of cellular defense against pathogen infections ranging from bacteria to Metazoa. These pathways are activated following the recognition of pathogen associated molecular patterns (PAMPs) by membrane and cytosolic… read more here.
Keywords: guanosine monophosphate; cgas; monophosphate adenosine; cyclic guanosine ... See more keywords
The cyclic guanosine monophosphate synthase-stimulator of interferon genes pathway as a potential target for tumor immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1121603
Abstract: Cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) synthase (cGAS) detects infections or tissue damage by binding to microbial or self-DNA in the cytoplasm. Upon binding DNA, cGAS produces cGAMP that binds to and activates the adaptor protein… read more here.
Keywords: cyclic guanosine; monophosphate; guanosine monophosphate; interferon genes ... See more keywords