Prodrugs of Nucleoside 5'-Monophosphate Analogues: Overview of the Recent Literature Concerning their Synthesis and Applications.
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DOI: 10.2174/0929867329666220909122820
Abstract: Nucleoside analogues are widely used as anti-infectious and antitumoral agents. However, their clinical use may face limitations associated with their physico-chemical properties, pharmacokinetic parameters, and/or their peculiar mechanisms of action. Indeed, once inside the cells,… read more here.
Keywords: nucleoside analogues; prodrugs nucleoside; nucleoside monophosphate; recent literature ... See more keywords