Monophthalates of betulinic acid and related pentacyclic triterpenes inhibit efficiently the SOS-mediated nucleotide exchange and impact PI3K/AKT signaling in oncogenic K-RAS4B proteins
Sign Up to like & getrecommendations! Published in 2025 at "RSC Advances"
DOI: 10.1039/d4ra08503e
Abstract: Betulinic acid and other herbal pentacyclic triterpenes have attracted interest in cancer research as these natural products induce apoptosis and suppress tumor progression. However, the molecular basis of the antitumor effect is still unknown. Here… read more here.
Keywords: monophthalates betulinic; betulinic acid; acid related; triterpenes inhibit ... See more keywords