Articles with "monosubstituted trans" as a keyword



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Divergent and Diastereoselective Synthesis of α-Monosubstituted and trans-α,β-Disubstituted γ-Lactams from (S)-N,N-Dibenzyl-α-amino Aldehydes via Henry and Michael Reactions

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Published in 2020 at "Synthesis"

DOI: 10.1055/s-0040-1706423

Abstract: γ-Monosubstituted and trans-α,β-disubstituted γ-lactams were diastereoselectively synthesized from common intermediates (S)-N,N-dibenzylated aldehydes derived from natural l -(α)-amino acids, employing a divergent approach. The key features of the routes include diastereoselective Henry and Michael reactions that… read more here.

Keywords: amino; michael reactions; trans disubstituted; henry michael ... See more keywords