Monoterpenoid indole alkaloids from the leaves of Alstonia scholaris and their NF-κB inhibitory activity.
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DOI: 10.1016/j.fitote.2017.10.018
Abstract: Four new monoterpenoid indole alkaloids (MIAs), scholarisines P-S (1-4), and 14 known MIAs (5-18) were isolated from the leaves of Alstonia scholaris (L) R. Br. (Apocynaceae). Their structures were elucidated by analyzing their HRESIMS data… read more here.
Keywords: alstonia scholaris; leaves alstonia; indole alkaloids; inhibitory activity ... See more keywords
Monoterpenoid indole alkaloids from the stems of Kopsia officinalis.
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DOI: 10.1016/j.fitote.2020.104547
Abstract: Five new indole alkaloids, kopsiofficines H-L (1-5), along with fourteen known alkaloids (6-19) were isolated from the stems of Kopsia officinalis. Their structures were elucidated by extensive NMR, mass spectroscopic analyses and comparison to the… read more here.
Keywords: stems kopsia; indole alkaloids; kopsia officinalis; alkaloids stems ... See more keywords
Metabolic profiling of monoterpenoid indole alkaloids from Tabernaemontana catharinensis (A. DC) latex by GC-MS
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DOI: 10.1016/j.phytol.2020.09.023
Abstract: Abstract Latex from Tabernaemontana catharinensis contains synthesized bioactive compounds known as monoterpenoid indole alkaloids (MIAs). Such compounds have several biological activities, including as cholinesterase inhibitors, and have analgesic, anti-inflammatory, bactericidal, antileishmanial, antitumoral andestrogenic properties, as… read more here.
Keywords: tabernaemontana catharinensis; catharinensis latex; indole alkaloids; catharinensis ... See more keywords
Alstobrogaline, an unusual pentacyclic monoterpenoid indole alkaloid with aldimine and aldimine-N-oxide moieties from Alstonia scholaris
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DOI: 10.1016/j.tetlet.2019.02.018
Abstract: Abstract Alstobrogaline ( 1 ), an unusual monoterpenoid indole alkaloid incorporating a third N atom and possessing two aldimine functions, with one being in the form of N -oxide, was isolated from the leaves of… read more here.
Keywords: indole alkaloid; aldimine; alstonia scholaris; monoterpenoid indole ... See more keywords
Three new monoterpenoid indole alkaloids from Alstonia rostrata
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DOI: 10.1016/j.tetlet.2021.153180
Abstract: Abstract Three new monoterpenoid indole alkaloids, alstratines A–C (1–3), along with three known ones were isolated from Alstonia rostrata. Compound 2 is the first example of an akuammicine-type alkaloid possessing an unprecedented 6/5/6/5/6/5 hexacyclic ring… read more here.
Keywords: alstonia rostrata; indole alkaloids; new monoterpenoid; monoterpenoid indole ... See more keywords
Uncarialins A-I, Monoterpenoid Indole Alkaloids from Uncaria rhynchophylla as Natural Agonists of the 5-HT1A Receptor.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.9b00532
Abstract: Nine new monoterpenoid indole alkaloids, uncarialins A-I (1-9), were isolated from Uncaria rhynchophylla as well as 14 known analogues (10-23). Their structures were determined by HRESIMS, 1D and 2D NMR, and experimental and calculated electronic… read more here.
Keywords: ht1a receptor; uncaria rhynchophylla; indole alkaloids; uncarialins monoterpenoid ... See more keywords
Ophiorrhines A and B, Two Immunosuppressive Monoterpenoid Indole Alkaloids from Ophiorrhiza japonica.
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DOI: 10.1021/acs.orglett.8b03489
Abstract: Two monoterpenoid indole alkaloids, ophiorrhines A (1) and B (2), were obtained from plant Ophiorrhiza japonica BI. Their structures were elucidated by extensive spectroscopic methods and single crystal X-ray diffraction. Compounds 1 and 2 possess… read more here.
Keywords: two immunosuppressive; indole alkaloids; immunosuppressive monoterpenoid; ophiorrhines two ... See more keywords
Cytotoxic monoterpenoid indole alkaloids from the aerial parts of Kopsia officinalis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2019.1621851
Abstract: Abstract Three new monoterpenoid indole alkaloids, kopsiaofficines A–D (1–3), were isolated from the 95% EtOH extract of the aerial parts of Kopsia officinalis. Their structures were established on the basis of spectroscopic data. The isolated… read more here.
Keywords: indole alkaloids; kopsia officinalis; parts kopsia; monoterpenoid indole ... See more keywords
Two new aspidosperma-type monoterpenoid indole alkaloids from Ervatamia officinalis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2022.2090345
Abstract: Abstract Two new aspidosperma-type monoterpenoid indole alkaloids, 16-O-methylvoafinine (1) and 14,15-diepi-voafinidine (2) were isolated from the aerial parts of Ervatamia officinalis. Their structures were established by comprehensive spectroscopic analysis including 1D and 2D NMR, HR-ESI-MS,… read more here.
Keywords: monoterpenoid indole; indole alkaloids; type monoterpenoid; two new ... See more keywords
Two new monoterpenoid indole alkaloids from Mappianthus iodoides stems.
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DOI: 10.1080/14786419.2021.1928119
Abstract: Two previously unreported monoterpenoid indole alkaloids, 19(20)E-5-carboxymethylvallesiachotamine (1) and 19(20)Z-5-carboxymethylvallesiachotamine (2), along with five known indole alkaloids (3-7) were isolated from Mappianthus iodoides stems. Their structures were characterized by extensive spectroscopic data. Among these isolates,… read more here.
Keywords: two new; mappianthus iodoides; indole alkaloids; iodoides stems ... See more keywords
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit β-Amyloid42 Production and Phospho-Tau (Thr217)
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DOI: 10.3390/ijms24021487
Abstract: Eleven monoterpenoid indole alkaloids, including three new ones, tabercrassines A–C (1–3), were isolated from the seeds of Tabernaemontana crassa. Tabercrassine A (1) is an ibogan–ibogan-type bisindole alkaloid which is formed by the polymerization of two… read more here.
Keywords: phospho tau; monoterpenoid indole; indole alkaloids; production ... See more keywords